Tenofovir-lamivudine-efavirenz is a combination medication used in the treatment of HIV (human immunodeficiency virus) infection. It contains three antiretroviral drugs: tenofovir, lamivudine, and efavirenz. This combination therapy is commonly prescribed to suppress viral replication, reduce the viral load, and improve the immune function of individuals living with HIV.

Tenofovir-lamivudine-efavirenz belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs) and nucleoside reverse transcriptase inhibitors (NRTIs). These medications work by inhibiting the reverse transcriptase enzyme, which is necessary for the replication of the virus.


Tenofovir-lamivudine-efavirenz is effective against both HIV-1 and HIV-2, the two main strains of the virus. It is typically used as a first-line treatment option in combination with other antiretroviral drugs to form a comprehensive and potent treatment regimen.

The dosage and treatment duration of tenofovir-lamivudine-efavirenz may vary depending on factors such as the individual’s viral load, CD4 cell count, and treatment history. Regular monitoring of viral load, CD4 cell count, and liver function is important to assess treatment response and manage any potential side effects.


Like any medication, tenofovir-lamivudine-efavirenz can have potential side effects. Common side effects may include dizziness, drowsiness, rash, abnormal dreams, and changes in liver function tests. It is important to report any persistent or severe side effects to a healthcare professional.

Adherence to the prescribed treatment regimen is crucial for successful outcomes in HIV management. Missing doses or stopping treatment without medical advice can lead to the development of drug resistance and treatment failure.


Tenofovir-lamivudine-efavirenz may interact with other medications, so it is important to inform the healthcare provider about all the medications being taken, including over-the-counter drugs and supplements.

In summary, tenofovir-lamivudine-efavirenz is a combination medication used in the treatment of HIV infection. It contains three antiretroviral drugs that work together to suppress viral replication and reduce the viral load. Regular monitoring, adherence to the treatment regimen, and close communication with healthcare professionals are important for successful management of HIV.