Tegafur-uracil is a combination medication used in the treatment of certain types of cancer, including colorectal cancer and gastric cancer. It consists of tegafur, a chemotherapy drug, and uracil, which enhances the effectiveness of tegafur.

When tegafur is metabolized in the body, it is converted into an active form that helps to inhibit the growth of cancer cells. Uracil works by blocking an enzyme that breaks down tegafur, allowing higher levels of the active form to remain in the body for a longer duration.


Tegafur-uracil is typically administered orally in the form of capsules or tablets. The specific dosage and treatment regimen may vary depending on the type and stage of cancer, as well as individual factors.

As with any medication, tegafur-uracil can have side effects. Common side effects may include nausea, vomiting, diarrhea, loss of appetite, and fatigue. It is important to discuss any concerning or severe side effects with a healthcare provider.


Tegafur-uracil may interact with other medications, so it is crucial to inform the healthcare provider about all current medications, including over-the-counter drugs and supplements, before starting treatment.

Regular follow-up visits and monitoring by the healthcare team are important to assess the response to treatment and manage any potential side effects. Adherence to the prescribed treatment plan and open communication with the healthcare provider are crucial for successful treatment outcomes.

In summary, tegafur-uracil is a combination medication used in the treatment of certain types of cancer. It consists of tegafur and uracil, working together to inhibit the growth of cancer cells. Close monitoring and communication with healthcare providers are essential during treatment to manage side effects and ensure optimal outcomes.