Fulvestrant is a medication used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs known as selective estrogen receptor downregulators (SERDs).

Fulvestrant works by binding to estrogen receptors in breast cancer cells, blocking the effects of estrogen and inhibiting the growth of cancer cells. It also promotes the degradation of estrogen receptors, further reducing their activity.


The medication is typically administered through intramuscular injection. The dosage and treatment duration depend on the specific characteristics of the breast cancer, as well as the individual’s overall health.

Common side effects of fulvestrant may include hot flashes, injection site reactions, nausea, and fatigue. More serious side effects, such as liver problems, can occur but are less common. Regular monitoring of liver function may be recommended during treatment.


Fulvestrant should only be used under the guidance and prescription of a qualified healthcare professional experienced in the treatment of breast cancer. It may interact with other medications, so it is important to inform the healthcare provider about all medications being taken, including over-the-counter drugs and supplements.

In summary, fulvestrant is a medication used in the treatment of hormone receptor-positive breast cancer. It blocks estrogen receptors in cancer cells to inhibit their growth. Regular monitoring and adherence to healthcare provider instructions are important during fulvestrant treatment.

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