Dactinomycin, also known as actinomycin D, is a medication used in the treatment of various types of cancer, including Wilms’ tumor, rhabdomyosarcoma, and Ewing sarcoma. It belongs to a class of drugs known as antineoplastic antibiotics.

Dactinomycin works by interfering with the DNA replication process in cancer cells. It binds to the DNA molecule, preventing its normal function and inhibiting the synthesis of RNA and proteins necessary for cell growth and division. This ultimately leads to the death of the cancer cells.

The medication is typically administered intravenously. It may be used alone or in combination with other chemotherapy drugs, depending on the specific type and stage of cancer being treated.

Common side effects of dactinomycin may include nausea, vomiting, hair loss, decreased blood cell counts, and increased susceptibility to infections. More serious side effects, such as kidney or liver problems, can occur but are less common. Regular monitoring of blood cell counts and organ function may be recommended during treatment.

Dactinomycin should only be used under the guidance and prescription of a qualified healthcare professional experienced in the treatment of cancer. It may interact with other medications, so it is important to inform the healthcare provider about all medications being taken, including over-the-counter drugs and supplements.

In summary, dactinomycin is a medication used in the treatment of various types of cancer. It interferes with DNA replication in cancer cells to inhibit their growth and division. Regular monitoring and adherence to healthcare provider instructions are important during dactinomycin treatment.

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