All Trans Retinoic Acid

All-trans retinoic acid (ATRA) is a medication derived from vitamin A and is used in the treatment of certain types of cancer, specifically acute promyelocytic leukemia (APL).

ATRA works by promoting the maturation of abnormal cancer cells in APL. It helps to restore normal cell development and function, leading to the suppression of cancer growth.


The medication is typically prescribed as part of a combination treatment regimen that may include chemotherapy and other targeted therapies. The specific dosage and duration of treatment are determined by the healthcare provider based on individual factors and the response to therapy.

Common side effects of ATRA may include dry skin, mouth sores, headaches, nausea, and bone pain. In some cases, it can cause more serious side effects such as liver toxicity or blood clotting problems. Regular monitoring of blood cell counts, liver function, and other parameters is usually recommended during treatment.


ATRA should only be used under the supervision and prescription of a qualified healthcare professional experienced in the treatment of cancer. It is important to follow the prescribed dosage and schedule, as well as to communicate any concerns or side effects to the healthcare provider.

In summary, all-trans retinoic acid is a medication used in the treatment of acute promyelocytic leukemia. It promotes the maturation of abnormal cancer cells and helps to suppress cancer growth. Regular monitoring and adherence to healthcare provider instructions are important for successful treatment outcomes.


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